스티븐스, 피터 제이.,스틸웰, 레지날드,사우다드, 매튜 제임스,사마니에고, 아드리안 씨.
申请号：
KR1020187029641
公开号：
KR1020180127641A
申请日:
2017.03.16
申请国别(地区):
KR
年份:
2018
代理人:
摘要：
Provided in this disclosure are various composite grafts having a trabecular scaffold with voids defined in at least a portion of the scaffold and a biological component positioned in at least some of the voids of the scaffold. The grafts may have a synthetic scaffold or a bone substrate scaffold. The grafts may be osteogenic, chondrogenic, osteochondrogenic, or vulnerary in nature. Also provided are methods of using the composite grafts to treat a tissue defect in a subject. Methods of manufacturing are also provided. Synthetic scaffolds are manufactured by additive manufacturing. Agitation is used to combine the biological component with the scaffold of the graft.
