Agency for Science, Technology and Research;Nanyang Technological University;National University of Singapore
发明人:
Young-Tae Chang,Jun-Young Kim,Sahu Srikanta,Michael Christian Givskov,Liang Yang
申请号：
US15568727
公开号：
US10416153B2
申请日:
2016.04.20
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to a family of fluorescent compounds based on the BODIPY scaffold, and methods for the preparation of said compounds. The present invention further relates to the use of said compounds for the detection of bacterial biofilms, wherein the bacterial biofilm comprises Pseudomonas aeruginosa and the compound specifically binds to a Fap protein of Pseudomonas aeruginosa, or wherein the compound specifically binds to bacterial cells that contain high levels of cyclic-di-guanosine-monophosphate (c-di-GMP).
