Tom Yao-Hsiang Wu,Yongkai Li,Alex Cortez,Yefen Zou,Pranab Mishra,Xiaoyue Zhang,Nicholas Valiante
申请号：
US13867752
公开号：
US08895577B2
申请日:
2013.04.22
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors, including TLR7 and TLR8. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine (formula I) wherein: X3 is N； X4 is N Or CR3； X5 is —CR4═CR5.
