WU TOM YAO-HSIANG,WU Tom Yao-Hsiang,LI YONGKAI,LI Yongkai,CORTEZ ALEX,CORTEZ Alex,ZOU YEFEN,ZOU Yefen,MISHRA PRANAB,MISHRA Pranab,ZHANG XIAOYUE,ZHANG Xiaoyue,SKIBINSKI DAVID,SKIBINSKI David,SINGH MANM
申请号：
SI200931254
公开号：
SI2268618T1
申请日:
2009.02.27
申请国别(地区):
SI
年份:
2015
代理人:
摘要：
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors, including TLR7 and TLR8. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine (formula I) wherein: X3 is N X4 is N Or CR3 X5 is -CR4=CR5.
