PROBLEM TO BE SOLVED: To provide a peripheral vascular resistance estimation method that can improve estimate accuracy.SOLUTION: A peripheral vascular resistance estimation method is provided for estimating a peripheral vascular resistance by using an electrical circuit model. In the peripheral vascular resistance estimation method: a value of a radius artery pressure vp by the calculation using an equation of the electrical circuit model is compared with a value of a radial artery pressure vp obtained by the measurement while values of an attenuation constant α, an angular frequency ω, an amplitude coefficient B, and a time coefficient tb in the equation are changed and optimal solutions of the attenuation constant α, the angular frequency ω, the amplitude coefficient B and the time coefficient tb for minimizing an average mean square error between the value vp of the radial artery pressure obtained by the calculation and the value vp of the radial artery pressure obtained by the measurement are determined from the comparison, wherein the processing for (1) performing multiple times of search about each of α, ω, B, and tb, (2) using several sampling values in the search of each time, and (3) narrowing a searching area in the next search more than the last search is performed.SELECTED DRAWING: Figure 6COPYRIGHT: (C)2016,JPO&INPIT【課題】推定精度を向上することができる末梢血管抵抗推定方法を提供する。【解決手段】電気回路モデルを用いて末梢血管抵抗を推定する末梢血管抵抗推定方法において、電気回路モデルの式の減衰定数α、角周波数ω、振幅係数B、時間係数tbの値を変化させて前記式を用いた計算により得た橈骨動脈圧vpの値と、測定により得た橈骨動脈圧vpの値と、を比較し、前記計算により得た橈骨動脈圧の値vpと前記測定により得た橈骨動脈圧の値vpとの平均二乗誤差を最小化する減衰定数α、角周波数ω、振幅係数B、時間係数tbの最適解を決定するにあたって、(i)前記α、ω、B、tbのそれぞれについて複数回の探索を行う、(ii)各回の探索では複数のサンプリング値を用いる、(iii)次回の探索では前回の探索よりも探索範囲を狭める、の処理を行う。【選択図】図6
