1. A compound having a chemical structure of formula I, or a pharmaceutically acceptable salt, hydrate or solvate thereof, wherein: X is —N = or —C (R) =； Y is selected from the group consisting of fluoro, chloro, bromo, iodo, lower alkyl, lower alkoxy, haloalkyl, CN, —OH, cycloalkyl, —OR and —N (R) (R)； where: R is hydrogen, and R is selected from the group consisting of (i) hydrogen, —OR and lower alkyl, optionally substituted with one or more R； (ii) cycloalkyl or cycloalkylalkyl, each of which is optionally substituted with one or more R； (iii) heterocycloalkyl or heterocycloalkylalkyl, each of which is optionally substituted with one or more R； (iv) aryl or arylalkyl, each of which is optionally substituted with one or more R, and optionally two adjacent R groups on the aryl ring taken together form a 5- or 6-membered heterocyclic aromatic ring containing 1-4 heteroatoms selected from O or N ； and (v) heteroaryl or heteroarylalkyl, each of which is optionally substituted with one or more R； or R and Roba mean lower alkyl； or R and R are combined with the nitrogen atom to which they are attached to form a 3-7 membered ring containing 0-1 additional heteroatoms in the ring selected from O, N or S, wherein the nitrogen or sulfur atom is optionally oxidized； R is selected from the group consisting of from lower alkyl, haloalkyl, haloalkoxy, fluoro substituted lower alkyl, cycloalkyl optionally substituted with one or more R, heterocycloalkyl, monoalkylamino, dialkylamino, cycloalkylamino, heterocycloalkylamino, aryl optionally substituted with one or more E R, and heteroaryl optionally substituted with1. Соединение, имеющее химическую структуру формулы I,или его фармацевтически приемлемая соль, гидрат или сольват,где:X означает -N= или -C(R)=；Y выбран из группы, состоящей из фтора, хлора, брома, йода, низшего алкила, низшей алкоксигруппы, галогеналкила, CN, -OH, циклоалкила, -ORи -N(R)(R)； где:Rозначает водород, и Rвыбран из группы, состоящей из (i) водорода, -ORи
