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COMPOSITIONS AND METHODS FOR INHIBITING THE ACTIVITY OF LAR FAMILY PHOSPHATASES
专利权人:
CASE WESTERN RESERVE UNIVERSITY
发明人:
Bradley T. Lang,Jared M. Cregg,Jerry Silver,Yi-Lan Weng
申请号:
US15949967
公开号:
US20180228905A1
申请日:
2018.04.10
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A method of inhibiting and/or reducing the activity, signaling, and/or function of leukocyte-common antigen related (LAR) family of phosphatases in a cell of a subject induced by proteoglycans includes administering to the cell a therapeutic agent that inhibits one or more of catalytic activity, signaling, and function of the LAR family phosphatases without inhibiting binding to or activation the LAR family phosphatases by the proteoglycans.
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