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Sulfamic acid ester compounds useful in the inhibition of steroid sulphatase activity and aromatase activity
专利权人:
Barry Victor Lloyd Potter
发明人:
Barry Victor Lloyd Potter,Michael John Reed,Lok Wai Lawrence Woo,Atul Purohit,Christian Burbert,Paul Michael Wood,Oliver Brook Sutcliffe
申请号:
US11603941
公开号:
US08148415B2
申请日:
2006.11.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to steroid sulphatase and/or aromatase inhibitors of Formula III or Formula IV, wherein A is selected from H, OH, halogen and hydrocarbyl D, E and F are each independently of each other an optional linker group P, Q and R are independently of each other a ring system, wherein R4 and R5 are independently selected from H, alkyl, cycloalkyl, alkenyl, acyl and aryl, or combinations thereof, or together represent alkylene, wherein the or each alkyl or cycloalkyl or alkenyl or optionally contain one or more hetero atoms or groups, and which can be used in medicine.
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