The invention relates to a compound of the general formula (II) or its salt or solvate, as well as to medical use, which provides for them, where Awibran is from the group consisting of N and C-R； A selected from the group consisting of N and C — R； A selected from the group consisting of N and C — R； A, and A, and An are independently selected from the group consisting of N and C — R； R is selected from the group consisting of hydrogen, (C-C) alkyl, halogen, (C-C) alkoxy and (C-C) haloalkyl； R is selected from the group consisting of hydrogen, halogen, and (C-C) alkyl； R selected from the group consisting of hydrogen, (CC) alkyl, NRR, (CC) alkyl-NRR and cyano, where R and R are independently selected from the group consisting of hydrogen, (CC) cycloalkyl, (CC) heterocycloalkyl and (CC) alkyl, or Together with the nitrogen atom to which they are attached, R 5 and R 5 form a 5–7 membered heterocyclic ring, optionally containing in addition to the above nitrogen atom an additional heteroatomic group selected from the group consisting of O and NR, where R is selected from the group consisting of hydrogen , methyl, acetyl and formyl； Y is selected from the group consisting of O and S； R is selected from the group consisting of (C-C) alkyl, (C-C) cycloalkyl and (C-C) heterocycloalkyl； and R is selected from the group consisting of hydrogen, (C-C) alkyl and (C-C) alkoxy； however, certain specific compounds are excluded according to the condition, and to methods for producing these compounds.Изобретение относится к соединению общей формулы (II) или его соли или сольвату, а также к применению в медицине, которое их предусматривает,где А1 выбран из группы, состоящей из N и C-R8； A2 выбран из группы, состоящей из N и C-R3； A3 выбран из группы, состоящей из N и C-R9； A4, и A5, и A6 независимо выбраны из группы, состоящей из N и C-R1； R1 выбран из группы, состоящей из водорода, (C1-C3)алкила, галогена, (C1-C3)алкокси и (C1-C3)галогеналкила； R2 выбран из группы, состоящей из вод
