DIZIO, JAMES P.,,JOHNSON, ELIZABETH E.,,WU, ZHENG ZHI,,PRESZLER PRINCE, AMY,
申请号:
SG2013004783
公开号:
SG187158A1
申请日:
2011.07.19
申请国别(地区):
SG
年份:
2013
代理人:
摘要:
A stable transdermal adhesive composition comprising: an adhesive comprising a washed polymerization reaction product of at least two ethylenically unsaturated monomers; and at least one pharmaceutically active compound which is susceptible to oxidative degradation; wherein the at least two ethylenically unsaturated monomers, if present in the adhesive as unreacted monomers, are present at a level of less than 200 ppm of total unreacted monomer, based upon the total weight of the adhesive, methods of making the composition, a transdermal drug delivery device using the composition, methods of making the device, and methods of delivery the pharmaceutically active compound are provided.