James P. DiZIO,Elizabeth E. JOHNSON,Zheng Z. WU,Amy PRESZLER PRINCE
申请号：
US16042361
公开号：
US20180325838A1
申请日:
2018.07.23
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A stable transdermal adhesive composition comprising: an adhesive comprising a washed polymerization reaction product of at least two ethylenically unsaturated monomers； and at least one pharmaceutically active compound which is susceptible to oxidative degradation； wherein the at least two ethylenically unsaturated monomers, if present in the adhesive as unreacted monomers, are present at a level of less than 200 ppm of total unreacted monomer, based upon the total weight of the adhesive, methods of making the composition, a transdermal drug delivery device using the composition, methods of making the device, and methods of delivery the pharmaceutically active compound are provided.
