Gaston Stanislas Marcella Diels,Marc Gustaaf Celine Verdonck,Peter Jacobus Johannes Antonius Buijnsters,Kristof Van Emelen
申请号：
US12663158
公开号：
US08338422B2
申请日:
2008.06.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to compounds or pharmaceutically-acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy. The invention particularly relates to certain indolin-2-ones and aza-indolin-2-ones which possess anti-tumor activity and are accordingly useful in methods of treatment of the human or animal body, in particular such compounds are useful in the treatment of pathological processes which involve an aberrant cellular proliferation, such as tumor growth, rheumatoid arthritis, restenosis and atherosclerosis.
