DIELS, GASTON STANISLAS MARCELLA,TEN HOLTE, PETER,FREYNE, EDDY JEAN EDGARD,GRAND-PERRET, THIERRY ANDRE REGIS,VAN EMELEN, KRISTOF,EMBRECHTS, WERNER CONSTANT JOHAN,BONNET, PASCAL GHISLAIN ANDRE
申请号：
CA2693715
公开号：
CA2693715C
申请日:
2008.07.25
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention relates to compounds or pharmaceutically-acceptablesalts thereof, processes for preparingthem, pharmaceutical compositions containing them and their use in therapy.The invention particularly relates to compounds thatare polo-like kinase (PLKs) inhibitors useful for the treatment of diseasestates mediated by PLK, especially PLK4, in particularsuch compounds that are useful in the treatment of pathological processeswhich involve an aberrant cellular proliferation, such astumour growth, rheumatoid arthritis, restenosis and atherosclerosis.
