DIELS, GASTON STANISLAS MARCELLA,TEN HOLTE, PETER,FREYNE, EDDY JEAN EDGARD,GRAND-PERRET, THIERRY ANDRE REGIS,VAN EMELEN, KRISTOF,EMBRECHTS, WERNER CONSTANT JOHAN,BONNET, PASCAL GHISLAIN ANDRÉ
申请号：
DK08775359
公开号：
DK2185562T3
申请日:
2008.07.25
申请国别(地区):
DK
年份:
2016
代理人:
摘要：
The present invention relates to compounds or pharmaceutically-acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy. The invention particularly relates to compounds that are polo-like kinase (PLKs) inhibitors useful for the treatment of disease states mediated by PLK, especially PLK4, in particular such compounds that are useful in the treatment of pathological processes which involve an aberrant cellular proliferation, such as tumor growth, rheumatoid arthritis, restenosis and atherosclerosis.
