PROBLEM TO BE SOLVED: To provide a new differentiation inducing method for an epidermal keratinocyte.SOLUTION: A method for differentiation induction of a fat tissue-derived stem cell to an epidermal keratinocyte progenitor is characterized in that a fat tissue-derived stem cell is cultured in the presence of a fibroblast, a retinoic acid and a bone morphogenetic protein 4.COPYRIGHT: (C)2016,JPO&INPIT【課題】新たな表皮角化細胞の分化誘導法の提供。【解決手段】脂肪組織由来幹細胞を、線維芽細胞、レチノイン酸及び骨形成タンパク質4の存在下に培養することを特徴とする脂肪組織由来幹細胞の表皮角化前駆細胞への分化誘導方法。【選択図】なし