Direct reverse differentiation method from urine cell to keratinocyte stem cell and method for producing composition for promoting skin regeneration utilizing reverse differentiated keratinocyte stem cell
The present invention relates to a reverse regeneration inducing method for introducing a reverse differentiation factor Bmi1 and dnp63a to a reverse differentiation inducing method of keratinocyte stem cells from urine cells and a composition for promoting a skin regeneration promoting an induced reverse differentiated keratinocyte stem cell culture medium.本発明は、逆分化因子Bmi1およびdNP63aを導入して尿細胞からケラチノサイト幹細胞の逆分化誘導方法および誘導された逆分化ケラチノサイト幹細胞コンデイションド培地を有効成分とする皮膚再生促進用組成物に関する。