PROBLEM TO BE SOLVED: To provide a technique for simulating the behavior of epidermal tissues on the basis of actual conditions such as an age.SOLUTION: A simulation apparatus for epidermal tissues successively generates new keratinocyte models indicating prickle cells according to an acquired arbitrary division rate, respectively changes thicknesses of the respective keratinocyte models according to a cell thickness reduction rate corresponding to cell kinds of the respective keratinocyte models and elapsed time after the generation of the respective keratinocyte models, respectively changes the cell kinds of the respective keratinocyte models in the order of the prickle cells, granular cells and horny layer cells on the basis of the thicknesses of the respective keratinocyte models or the elapsed time of the respective keratinocyte models, and includes a peeling setting part for determining whether or not a barrier index total sum obtained by totaling barrier indexes indicating the height of a barrier performance of the keratinocyte model for all the keratinocyte models indicating the horny layer cells exceeds a prescribed threshold, and setting information stored in a cell model information storage part related to an object keratinocyte model to the state of being peeled from epidermal tissues.COPYRIGHT: (C)2013,JPO&INPIT【課題】表皮組織の挙動を年齢などの実態に即して模擬する技術を提供する。【解決手段】表皮組織シミュレーション装置は、取得された任意の分裂速度に応じて、有棘細胞を示す新たな角化細胞モデルを順次生成し、各角化細胞モデルの厚みを、各角化細胞モデルの細胞種別に応じた細胞厚の減少速度と各角化細胞モデルが生成されてからの経過時間とに応じてそれぞれ変化させ、各角化細胞モデルの厚み、又は、各角化細胞モデルの経過時間に基づいて、各角化細胞モデルの細胞種別を、有棘細胞、顆粒細胞、角層細胞の順にそれぞれ変化させ、角化細胞モデルのバリア性能の高さを示すバリア指数を角層細胞を示す全角化細胞モデルについて合計して得られるバリア指数総和が所定閾値を超えるか否かを判定し、対象の角化細胞モデルに関し細胞モデル情報記憶部に格納される情報を表皮組織から剥離された状態に設定する剥離設定部と、を有する。【選択図】図2
