PROBLEM TO BE SOLVED: To provide a compound exhibiting excellent antibacterial activity in wide pathogenic bacteria such as drug-resistant bacteria and plant pathogenic bacteria by inhibiting two component-regulating system of the bacteria, or enzyme-inhibiting activity to the enzyme possessed by the bacteria, to provide a method for producing the compound, to provide a microorganism of a producing microorganism of the compound, and to provide a composition, an antibacterial agent and an enzyme activity inhibitor, utilizing the compound.SOLUTION: The new enzyme activity inhibitor is produced by MK632-100F11 strain of Streptomyces sp. of accession number NITEP-777.COPYRIGHT: (C)2011,JPO&INPIT【課題】細菌の二成分制御系を阻害することにより、薬剤耐性菌、植物病原細菌等の幅広い病原性細菌に対し、優れた抗菌活性、若しくは、前記細菌の有する酵素に対し、酵素阻害活性を有する化合物、及びそれらの製造方法、並びに、前記化合物の生産菌である微生物、及び前記化合物を利用した化合物含有組成物、抗菌剤、及び酵素活性阻害剤の提供。【解決手段】受託番号NITEP-777のストレプトマイセス(Streptomycessp.)MK632-100F11株が生産する新規な酵素活性阻害剤。【選択図】なし