CHIMERIC ANTIGEN RECEPTORS FOR THE TREATMENT OF CANCER

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专利权人:

THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;NOVARTIS AG

发明人:

BRANNETTI, Barbara,BROGDON, Jennifer,ENGELS, Boris,GRANDA, Brian,HUANG, Lu,LEI, Ming,LI, Na,ZHANG, Jimin,GUIMARAES, Carla

申请号：

PH12019500750

公开号：

PH12019500750A1

申请日:

2019.04.05

申请国别(地区):

PH

年份:

2019

代理人:

摘要：

The invention provides compositions and methods for treating diseases associated with expression of CD20 or CD22. The invention also relates to chimeric antigen receptor (CAR) specific to CD20 or CD22, vectors encoding the same, and recombinant T or natural killer (NK) cells comprising the CD20 CAR or CD22 CAR. The invention also includes methods of administering a genetically modified T cell or NK cell expressing a CAR that comprises a CD20 or CD22 binding domain.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/