Ltd.;Asclepius (Suzhou) Technology Company Group Co.
发明人:
LI, Huashun,HAN, Kunkun,WANG, Baolei,REN, Baoyong
申请号：
AU2018378395
公开号：
AU2018378395A1
申请日:
2018.11.28
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
Provided are a nucleotide sequence encoding CAR, a ROBO1 CAR-NK cell expressing the CAR and a preparation method therefor and the use thereof. The ROBO1 CAR-NK cell provided is used for specifically killing tumour cells by applying the ROBO1 antibody, which uses the ROBO1 molecule as a target antigen, to the construction of the CAR-NK cell and utilizing the ROBO1 CAR-NK cell. The ROBO1 CAR-NK cell can be used as a therapeutic drug for tumour diseases and is used for treating tumours with high expression of the ROBO1 molecule.
