Inc.;University of Central Florida Research Foundation
发明人:
Parks, Griff,Copik, Alicja
申请号：
AU2018273963
公开号：
AU2018273963A1
申请日:
2018.05.25
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
Disclosed are engineered oncolytic viruses, related fusion proteins and polynucleotides encoding them, and methods for treating cancer using the engineered viruses. In one aspect, disclosed herein are engineered oncolytic viruses, wherein the oncolytic virus expresses one or more exogenous membrane bound immune cell targeting ligands comprising an uncleaved signal anchor.
