Ivar M. MCDONALD,Naidu S. CHOWDARI,Walter Lewis Johnson,Yong Zhang,Robert M. BORZILLERI,Sanjeev Gangwar
申请号：
US14994378
公开号：
US20160199510A1
申请日:
2016.01.13
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Benzodiazepine dimers having a structure represented bywherein X comprises a heteroaromatic moiety and is as further defined in the application； R1 isand the other variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used in an antibody-drug conjugate (ADC).
