The disclosure relates to uses of PD-1 antibody for treating tumor. Specifically, the disclosure relates to uses of PD-1 antibody, antigen-binding fragments in the preparation of drugs for treating tumor patients who have been previously treated with anti-CTLA-4 antibody, antigen-binding fragments thereof.本披露涉及PD-1抗體用於治療腫瘤的用途。具體而言,本披露涉及抗PD-1抗體或其抗原結合片段在製備治療曾接受抗CTLA-4抗體或其抗原結合片段治療的腫瘤患者的藥物中的用途。