COMPOSITIONS PHARMACEUTIQUES BASÉES SUR DES SUPERSTRUCTURES D'ANTAGONISTE/BLOQUEUR DU RÉCEPTEUR DE L'ANGIOTENSINE (ARB) ET DE L'INHIBITEUR DE L'ENDOPEPTIDASE NEUTRE (NEP)

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专利权人:

Novartis AG

发明人:

申请号：

EP16157767.1

公开号：

EP3067043A1

申请日:

2008.11.04

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

Solid oral dosage forms, especially tablets, of a pharmaceutical composition comprising a supramolecular complex can be formed from a direct compression process or a compaction process such as roller compaction. Such solid oral dosage forms feature an immediate release profile that allows for fast release of the therapeutic agent. A particularly useful supramolecular complex is trisodium [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl) propionate-(S)-3'-methyl-2'-(pentanoyl{2"-(tetrazol-5-ylate)biphenyl-4'-ylmethyl}amino)butyrate]hemipentahydrate.

来源网站：

中国工程科技知识中心

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