Liu Deng;Michael Fitzpatrick Wempe;Stephanie Kay Clendennen;Neil Warren Boaz
发明人:
Michael Fitzpatrick Wempe,Liu Deng,Stephanie Kay Clendennen,Neil Warren Boaz
申请号：
US12236171
公开号：
US08263094B2
申请日:
2008.09.23
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Esters of 4,5-disubstituted-oxy-2-methyl-3,6-dioxo-cyclohexa-1,4-dienyl alkyl acids were prepared chemically and/or enzymatically. Depending upon the ester, improved melanocyte cytotoxicity was achieved. Improved cytotoxicity characteristics are consistent with ester analogs being more physiologically compatible and less irritating to skin than their corresponding acids.
