ESTERS D'ACIDES OXY-2-MÉTHYL-3,6-DIOXO-CYCLOHEXA-1,4-DIÉNYLALKYLIQUES 4,5-DISUBSTITUÉS ET LEUR PRÉPARATION

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专利权人:

EASTMAN CHEMICAL COMPANY

发明人:

申请号：

EP09736700.7

公开号：

EP2344442B1

申请日:

2009.09.17

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

Esters of 4,5-disubstituted-oxy-2-methyl-3,6-dioxo-cyclohexa-1,4-dienyl alkyl acids were prepared chemically and/or enzymatically. Depending upon the ester, improved melanocyte cytotoxicity was achieved. Improved cytotoxicity characteristics are consistent with ester analogs being more physiologically compatible and less irritating to skin than their corresponding acids.

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