The utility model relates to an operating device of a combine harvester. The operating device can ensure the better recognizing capacity of operating switches for threshing depth adjustment which are arranged at the handheld part of an operating lever. Under the condition of small possibility of misoperation, a thumb which holds the operating lever can easily conduct operation. In the handheld part (40) of the operating lever which moves forwards and backwards, on the transverse side surface (44A) of an operating seat side in a horizontal direction, operating switches (42) for threshing depth adjustment are vertically and separately arranged. The operating switches (42) for threshing depth adjustment are arranged in a way that the pressing operating direction (a) of one operating switch (42) is a direction which is vertical and gets far away from the pressing operating direction (b) of the other operating switch (42), and the pressing operating direction (b) of the other operating switch (42) is a direction which is horizontal or vertical and gets far away from the pressing operating direction (a) of one operating switch (42).