The present invention relates to pyrrolo-6-membered heteroaromatic ring derivatives, preparation processes and pharmaceutical use thereof. Specifically, the present invention relates to pyrrolo-6-membered heteroaromatic ringderivatives of general formula (I), preparation processes and pharmaceutical use thereof, as well as their use as a therapeutic agent, especially their use as a JAK kinase inhibitor and an immunosupressant, wherein each substitute of general formula (I) is defined as those in the specification.本發明涉及吡咯并六員雜芳環類衍生物、其製備方法及其在醫藥上的應用。具體而言，本發明涉及一種通式(I)所示的新的吡咯并六元員雜芳環類衍生物、其製備方法及含有該衍生物的藥物組合物以及其作為治療劑，特別是作為JAK抑制劑和免疫抑制劑的用途，其中通式(I)的各取代基與說明書中的定義相同。
