GANYMED PHARMACEUTICALS AG;TRON - TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITATSMEDIZIN DER JOHANNEGUTENBERG-UNIVERSITAT MAINZ GEMEINNUTZIGE GMBH;TRON - TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ GEMEINNUTZIGE GMBH;BIONTECH AG
发明人:
SAHIN, UGUR,TURECI, OZLEM,WALTER, KORDEN,WAGNER, MEIKE,KREUZBERG, MARIA,HACKER, SABINE,JACOBS, STEFAN
申请号：
CA2919570
公开号：
CA2919570A1
申请日:
2014.07.30
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention provides methods for diagnosis or treatment of cancer diseases involving cancer stem cells comprising targeting CLDN6. In particular, the present invention provides a method of determining cancer stem cells comprising detecting cells expressing CLDN6, Furthermore, the present invention provides a method of treating or preventing cancer comprising inhibiting and/or eliminating cancer stem cells by administering an antibody having the ability of binding to CLDN6 to a cancer patient.
