DIAGNOSTICS AND TREATMENT OF CANCER ASSOCIATED WITH CANCER STEM CELLS农业专利-农业专业知识服务系统

专利权人:: БИОНТЕХ АГ (DE);Астеллас Фарма Инк. (JP);ТРОН - ТРАНСЛАЦИОНАЛЕ ОНКОЛОГИ АН ДЕР УНИВЕРЗИТЕТСМЕДИЦИН ДЕР ЙОХАННЕС ГУТЕНБЕРГ-УНИВЕРЗИТЕТ МАЙНЦ ГЕМАЙННЮТЦИГЕ ГМБХ (DE)

发明人:: САХИН, Угур (DE),ТЮРЕЧИ, Озлем (DE),ВАЛЬТЕР, Корден (DE),ВАГНЕР, Майке (DE),КРОЙЦБЕРГ, Мария (DE),ХЭКЕР, Сабине (DE),ЯКОБС, Штефан (DE)

摘要：: The present invention provides methods for diagnosis or treatment of cancer diseases involving cancer stem cells comprising targeting CLDN6. In particular, the present invention provides a method of determining cancer stem cells comprising detecting cells expressing CLDN6. Furthermore, the present invention provides a method of treating or preventing cancer comprising inhibiting and/or eliminating cancer stem cells by administering an antibody having the ability of binding to CLDN6 to a cancer patient.