Ganymed Pharmaceuticals AG;TRON - Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg-Universitat Mainz Gemeinnutzige GmbH;BioNTech AG
发明人:
Sahin, Ugur,Tureci, Ozlem,Walter, Korden,Wagner, Meike,Kreuzberg, Maria,Hacker, Sabine,Jacobs, Stefan
申请号：
AU2014298505
公开号：
AU2014298505A1
申请日:
2014.07.30
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
The present invention provides methods for diagnosis or treatment of cancer diseases involving cancer stem cells comprising targeting CLDN6. In particular, the present invention provides a method of determining cancer stem cells comprising detecting cells expressing CLDN6, Furthermore, the present invention provides a method of treating or preventing cancer comprising inhibiting and/or eliminating cancer stem cells by administering an antibody having the ability of binding to CLDN6 to a cancer patient.
