DIAGNOSIS AND TREATMENT OF CANCER ASSOCIATED WITH CANCER STEM CELLS农业专利-农业专业知识服务系统

专利权人:: ГАНИМЕД ФАРМАСЬЮТИКАЛЗ АГ (DE);БИОНТЕХ АГ (DE);ТРОН - ТРАНСЛАЦИОНАЛЕ ОНКОЛОГИ АН ДЕР УНИВЕРЗИТЕТСМЕДИЦИН ДЕР ЙОХАННЕС ГУТЕНБЕРГ-УНИВЕРЗИТЕТ МАЙНЦ ГЕМАЙННЮТЦИГЕ ГМБХ (DE)

发明人:: САХИН Угур (DE),ТЮРЕЧИ Озлем (DE),ВАЛЬТЕР Корден (DE),ВАГНЕР Майке (DE),КРОЙЦБЕРГ Мария (DE),ХЭКЕР Сабине (DE),ЯКОБС Штефан (DE)

摘要：: The present invention provides methods for diagnosis or treatment of cancer diseases involving cancer stem cells comprising targeting CLDN6. In particular, the present invention provides a method of determining cancer stem cells comprising detecting cells expressing CLDN6, Furthermore, the present invention provides a method of treating or preventing cancer comprising inhibiting and/or eliminating cancer stem cells by administering an antibody having the ability of binding to CLDN6 to a cancer patient.