NOVEL 3,4-DISUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINES AND 4,5-DISUBSTITUTED-7H-PYRROLO[2,3-C]PYRIDAZINES AS LRRK2 INHIBITORS

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专利权人:

发明人:

申请号：

EP14827274.3

公开号：

EP3083618B1

申请日:

2014.12.03

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

wherein R1, R2, R3, R4 and X are as defined in the specification. The invention is also directed to pharmaceutical compositions comprising the compounds of formula I and to use of the compounds in the treatment of diseases associated with LRRK2, such as neurodegenerative diseases including Parkinsons disease or Alzheimers disease, cancer, Crohns disease or leprosy.

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