GALATSIS, Paul,HENDERSON, Jaclyn Louise,KORMOS, Bethany Lyn,KURUMBAIL, Ravi G.,REESE, Matthew Richard,STEPAN, Antonia Friederike,VERHOEST, Patrick Robert,WAGER, Travis T.,PETTERSSON, Martin Youngjin,G
申请号：
EP16766633
公开号：
EP3350178A1
申请日:
2016.09.07
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
wherein R1, R1a, R1b, R2, R4, R5, R6, X and Z are as defined in the specification. The invention is also directed to pharmaceutical compositions comprising the compounds of Formula (I) and to use of the compounds in the treatment of diseases associated with LRRK2, such as neurodegenerative diseases including Parkinsons disease or Alzheimers disease, cancer, Crohns disease or leprosy.
