CHA, Mi Young,KANG, Seok Jong,KIM, Mi Ra,LEE, Ju Yeon,JEON, Ji Young,JO, Myoung Gi,KWAK, Eun Joo,LEE, Kwang Ok,HA, Tae Hee,SUH, Kwee Hyun,KIM, Maeng Sup
申请号：
ES11798350
公开号：
ES2622138T3
申请日:
2011.06.20
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A compound of formula (I) or a pharmaceutically acceptable salt thereof: ** Formula ** in which, W is O； X is O, NH, S, SO or SO2； Y is a hydrogen atom, halogen atom, C1-6 alkyl or C1-6 alkoxy； A and B are each independently a hydrogen atom, halogen atom, or di (C1-6 alkyl) aminomethyl； Z is aryl or heteroaryl having one or more substituents selected from the group consisting of: hydrogen atom, halogen atom, hydroxy, nitro, cyano, C1-6 alkyl, C1-6 alkoxy, C1-6 alkylcarbonyl, C1 alkoxy - 6carbonyl, di (C1-6 alkyl) aminoC2-6carbonyl amino, amino, C1-6 alkyl lamino, di (C1-6 alkyl) amino, carbamoyl, C1-6 alkylcarbamoyl, di (C1-6 alkyl) carbamoyl, di ( C1-6 alkyl) aminoC2-6carbamoyl, sulfamoyl, C1-6 alkyl sulfamoyl, di (C1-6 alkyl) sulfamoyl, di (C1-6 alkyl) aminoC2-6sulfamoyl alkyl, C1-6sulfonyl alkyl, C1-6sulfinyl alkyl, di (alkyl C1-6) phosphonyl, hydroxy C1-6 alkyl, hydroxycarbonylalkyl C1-6, alkoxy C1-6alkyl C1-6 alkyl C1-6 sulfonylalkyl C1-6, alkyl C1-6sulfinylalkyl C1-6, di (C1-6 alkyl) phosphonylalkyl C1 -6, 2-6 hydroxyalkoxy, C 1-6 alkoxy 2-6 alkoxy, C 1-6 aminoalkyl, C 1-6 alkylC 1-6 alkylalkyl, di (C 1-6 alkyl) C 1-6 aminoalkyl, di (C 1-6 alkyl) aminoacetyl, C2 aminoalkoxy -6, C1-6 alkyl C2-6 aminoalkoxy, di (alkyl C1-6) C2-6 aminoalkoxy, C2-6 hydroxyalkyl amino, C1-20 alkoxyC2-6amino, aminoC2-6aminoalkyl, C1-6alkylC2-6aminoalkyl, di (C1-6alkyl) aminoC2-6aminoalkyl, heteroaryl, heterocycle, heterocyclic oxy, heterocyclic thio, heterocyclic sulfinyl, heterocyclic sulfonyl, heterocyclic sulfamoyl, heterocyclic C1-6 alkyl, heterocyclic C1-6 alkoxy, heterocyclic amino, heterocyclic C1-6 alkylamino, heterocyclic carbonyl, heterocyclic alkyl 6 heterocyclic carbonyl, C1-6 heterocyclic carbonylalkyl, C1-6 alkylthio heterocyclic, C1-6 alkyl heterocyclic sulfinyl, C1-6 alkyl heterocyclic sulfonyl, heterocyclic aminocarbonyl, C1-6alinocarbonyl heterocyclic, aminocarbonylalkyl, heterocyclic C1-6 heterocyclic C1-6 alkyl heterocyclic carboxyamide； aryl refers to a C6-12 cy
