Phenyl pyrrole aminoguanidine derivatives

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专利权人:

SynAct Pharma ApS

发明人:

Boman, Arne,Jonassen, Thomas Engelbrecht Norkild,Lundstedt, Torbjörn

申请号：

ES11164583

公开号：

ES2571253T3

申请日:

2007.06.11

申请国别(地区):

ES

年份:

2016

代理人:

摘要：

A compound of general formula (I) ** Formula ** including tautomeric forms thereof, in which n is 1, 2 or 3； each R1, R2, R3, R4 10 and R5 is independently selected from the group consisting of hydrogen, optionally substituted C1-6 alkyl, optionally substituted C3-6 cycloalkyl, optionally substituted C2-6 alkenyl, optionally substituted C4-6 alkydienyl, optionally substituted C2-6 alkynyl, hydroxy, optionally substituted C1-6 alkoxy, optionally substituted C2-6 alkenyloxy, carboxy, optionally substituted C1-6 alkoxycarbonyl, optionally substituted C1-6 alkylcarbonyl, formyl, C1-6 alkylsulfonylamino, optionally substituted aryl, optionally substituted aryloxycarbonyl, optionally substituted aryloxy, optionally substituted arylcarbonyl, optionally substituted arylamino, arylsulfonylamino, optionally substituted heteroaryl, optionally substituted heteroaryloxycarbonyl, optionally substituted heteroaryloxy, optionally substituted heteroarylcarbonyl, optionally substituted heteroaryl, heteroarylsyl optionally substituted, optionally substituted heterocyclyloxycarbonyl, optionally substituted heterocyclyloxy, optionally substituted heterocyclylcarbonyl, optionally substituted heterocyclylamino, heterocyclylsulfonylamino, amino, mono- and di (C1-6 alkyl) amino, carbamoyl, mono- and di (C1-6 alkyl) amino -C 1-6 alkyl aminocarbonyl, mono- and di (C 1-6 alkyl) amino C 1-6 alkyl aminocarbonyl, C 1-6 alkylcarbonylamino, amino C 1-6 alkylcarbonylamino, mono- and di (C 1-6 alkyl) amino -C 1-6 alkylcarbonylamino, cyano, guanidino, carbamido, C 1-6 alkanoyloxy, C 1-6 alkyl sulfonyl, C 1-6 alkylsulfinyl, C 1-6 alkylsulfonyloxy, aminosulfonyl, mono- and di (C 1-6 alkyl) aminosulfonyl, nitro, optionally substituted C1-6 alkylthio and halogen, wherein any C1-6 alkyl attached to nitrogen is optionally substituted with hydroxy, C1-6 alkoxy, C2-6 alkenyloxy, amino, mono- and di (C1-6 alkyl) amino, carboxy, C 1-6 alkylcarbonylamino, halogen, C 1-6 alkylthio, C 1-6 alkyl sulfonylamino or gu

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