REGUEIRO-REN, ALICIA,SWIDORSKI, JACOB,SIT, SING-YUEN,CHEN, YAN,CHEN, JIE,MEANWELL, NICHOLAS A.,LIU, ZHENG
申请号：
CA2826257
公开号：
CA2826257A1
申请日:
2012.01.27
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-28 amines of C-3 modified betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors. These compounds are useful for the treatment of HIV and AIDS. In particular, the following compounds are provided herein, including pharmaceutically acceptable salts thereof: a compound of formula (I), a compound of formula (II), and a compound of formula (III).
