Yan Chen;Jie Chen;Jacob Swidorski;Sing-Yuen Sit;Alicia Regueiro-Ren;Zheng Liu;Nicholas A. Meanwell
发明人:
Alicia Regueiro-Ren,Jacob Swidorski,Sing-Yuen Sit,Yan Chen,Jie Chen,Nicholas A. Meanwell,Zheng Liu
申请号：
US13359680
公开号：
US08748415B2
申请日:
2012.01.27
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-28 amines of C-3 modified betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors. These compounds are useful for the treatment of HIV and AIDS. In particular, the following compounds are provided herein, including pharmaceutically acceptable salts thereof:a compound of formula Ia compound of formula IIand a compound of formula III
