Killeen, Kevin P.,Griffin IV, Thomas J.,Thanawastien, Ann
申请号：
AU2010292195
公开号：
AU2010292195A1
申请日:
2010.09.09
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention relates to immunogenic compositions containing an antigen of interest entrapped with a crosslinked carrier protein matrix, methods of making such vaccines, and methods of vaccine administration, wherein the immunogenicity of the protein matrix, and hence its effectiveness as a vaccine, is improved by controlling or selecting the particle size of the protein matrix particles to eliminate low molecular weight particles, e.g., less than 100 nm in diameter.
