SRINIVASA R. KARRA;LIZBETH CELESTE DE SELM;XU-LIANG JUANG;BENNY C. ASKEW JR.;ANDREAS GOUTOPOULOS;HENRY YU;MERCK PATENT GMBH
发明人:
ANDREAS GOUTOPOULOS,HENRY YU,LIZBETH CELESTE DE SELM,SRINIVASA R. KARRA,XU-LIANG JUANG,BENNY C. ASKEW JR.
申请号：
IL21158411
公开号：
IL211584A
申请日:
2011.03.06
申请国别(地区):
IL
年份:
2017
代理人:
摘要：
Macrocyclic derivative compounds that inhibit protein kinase enzymes are disclosed along with pharmaceutical compositions comprising these compounds and methods for synthesizing the same. Such compounds have utility in the treatment of proliferative diseases resulting from unregulated and/or disturbed kinase activity such as cancers, psoriasis, viral and bacterial infections, inflammatory and autoimmune diseases.
