AMANDA E. SUTTON,ANDREAS GOUTOPOULOS,BAYARD R. HUCK,SRINVASA R. KARRA,SRINVASA R. KARRA,XIAOLING CHEN,YUFANG XIAO
申请号:
BRPI0914936
公开号:
BRPI0914936A2
申请日:
2009.06.29
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
Naphthyridinone derivative compounds that inhibit Aurora kinase enzymes are disclosed along with pharmaceutical compositions comprising these compounds and methods for synthesizing the same. Such compounds have utility in the treatment of proliferative diseases resulting from unregulated and/or disturbed Aurora kinases such as cancers, psoriasis, viral and bacterial infections, inflammatory and autoimmune diseases.