ANDREAS GOUTOPOULOS;YUFANG XIAO;XIAOLING CHEN;MERCK PATENT GMBH;SRINIVASA R. KARRA;BAYARD R. HUCK;AMANDA E. SUTTON
发明人:
ANDREAS GOUTOPOULOS,YUFANG XIAO,XIAOLING CHEN,SRINIVASA R. KARRA,BAYARD R. HUCK,AMANDA E. SUTTON
申请号：
IL21037710
公开号：
IL210377A
申请日:
2010.12.30
申请国别(地区):
IL
年份:
2015
代理人:
摘要：
Naphthyridinone derivative compounds that inhibit Aurora kinase enzymes are disclosed along with pharmaceutical compositions comprising these compounds and methods for synthesizing the same. Such compounds have utility in the treatment of proliferative diseases resulting from unregulated and/or disturbed Aurora kinases such as cancers, psoriasis, viral and bacterial infections, inflammatory and autoimmune diseases.
