XIAO YUFANG,CHEN XIAOLING,KARRA SRINIVASA R,HUCK BAYARD R,SUTTON AMANDA E,GOUTOPOULOS ANDREAS
申请号:
ZA201008878
公开号:
ZA201008878B
申请日:
2010.12.09
申请国别(地区):
ZA
年份:
2012
代理人:
摘要:
Naphthyridinone derivative compounds that inhibit Aurora kinase enzymes are disclosed along with pharmaceutical compositions comprising these compounds and methods for synthesizing the same. Such compounds have utility in the treatment of proliferative diseases resulting from unregulated and/or disturbed Aurora kinases such as cancers, psoriasis, viral and bacterial infections, inflammatory and autoimmune diseases.