PROCEDES DE COMPLEXATION DE LA CYCLODEXTRINE POUR FORMULER DES INHIBITEURS DE PROTEASOMES DE PEPTIDES

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专利权人:

ONYX THERAPEUTICS; INC.

发明人:

LEWIS, EVAN,SHWONEK, PETER,DALZIEL, SEAN,JUMAA, MOUHANNAD

申请号：

CA2793894

公开号：

CA2793894A1

申请日:

2012.09.13

申请国别(地区):

CA

年份:

2013

代理人:

摘要：

This disclosure provides methods for formulating compositions comprising oneormore peptide proteasome inhibitors and a cyclodextrin, particularly asubstitutedcyclodextrin. Such methods substantially increase the solubility and stabilityof theseproteasome inhibitors and facilitate both their manufacture andadministration.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/