NATIONAL INSTITUTE OF HEALTH;DANA FARBER CANCER INSTITUTE
发明人:
WALENSKY, LOREN D.,TJANDRA, NICO,GAVATHIOTIS, EVRIPIDIS,SUZUKI, MOTOSHI,BIRD, GREGORY H.
申请号:
CA2700925
公开号:
CA2700925C
申请日:
2008.09.26
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention is based, at least in part, on the identification of anovel active site on BCL-2 familypolypeptide such as BAX, which when bound by a compound, modifies the activityof the BCL-2 family polypeptide.