A compound of formula (I): ** Formula ** in which: j and k are each independently 0, 1, 2 or 3； Q is -C (R1a) H-, -O-, -S (O) m- (where m is 1 or 2), -CF2-, -C (O) O-, -C (O) n (R5) - or -N (R5) C (O) -； R1a is -OR5； R1 is hydrogen, alkyl, alkenyl, alkynyl, haloalkyl, aryl, cycloalkyl, cycloalkylalkyl, heteroaryl, heterocyclyl, -R8-C (O) R6, -R8-C (O) OR5, -R8-C (O) n (R4 ) R5, -S (O) 2-R5, -R9-S (O) m-R5 (where m is 0, 1 or 2), -R8- OR5, -R8-CN, -R9-P ( O) (OR5) 2, or -R9-O-R9-OR5； or R1 is aralkyl substituted by -C (O) n (R6) R7 in which: R6 is hydrogen, alkyl, aryl or aralkyl； and R7 is hydrogen, alkyl, haloalkyl, -R9-CN, -R9-OR5, -R9-N (R4) R5, aryl, aralkyl, cycloalkyl, cycloalkylalkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, or heteroarylalkyl； or R6 and R7, together with the nitrogen to which they are attached, can form a heterocyclyl or heteroaryl； and wherein each aryl, aralkyl, cycloalkyl, cycloalkylalkyl, heterocyclyl, heterocyclylalkyl, heteroaryl and heteroarylalkyl group for R6 and R7 may be optionally substituted by one or more substituents selected from the group consisting of alkyl, cycloalkyl, aryl, aralkyl, halo, haloalkyl, -R8-CN, -R8-OR5, heterocyclyl and heteroaryl； or R1 is aralkyl optionally substituted by one or more substituents selected from the group consisting of -R8-OR5, -C (O) OR5, halo, haloalkyl, alkyl, nitro, cyano, aryl, aralkyl, heterocyclyl and heteroaryl； or R1 is -R9-N (R10) R11, -R9-N (R12) C (O) R11 or -R9-N (R10) C (O) n (R10) R11 in which: each R10 is hydrogen, alkyl, aryl, aralkyl or heteroaryl； each R11 is hydrogen, alkyl, haloalkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, heteroarylalkyl, -R9-OC (O) R5, -R9-C (O) OR5, -R9-C (O) n (R4) R5, -R9-C (O) R5, - R9-N (R4) R5, -R9-OR5, or -R9-CN； and R12 is hydrogen, alkyl, aryl, aralkyl or -C (O) R5； and wherein each aryl, aralkyl, cycloalkyl, cycloalkylalkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, and heteroarylalkyl g
