The present invention provides a compound represented by formula (I), a pharmaceutically acceptable salt thereof or a solvate thereof. (In the formula, each of A and Z independently represents CO, SO or SO 2 ； each of X and Y independently represents S or O； each of R 1 -R 4 independently represents hydrogen, alkyl, alkenyl, alkynyl or halo； each R 5 independently represents alkyl, alkenyl, alkynyl or halo； and n represents an integer of 0-4.) This compound is capable of specifically binding to an AMPA receptor, and shows extremely high brain uptake.本發明提供一種以下述式(I)所表示之化合物、其醫藥上可容許之鹽、或其溶劑合物。(式中，A及Z分別獨立，為CO、SO或SO2；X及Y分別獨立，為S或O；R1~R4分別獨立，為氫、烷基、烯基、炔基或鹵素；R5每次出現時分別獨立，為烷基、烯基、炔基或鹵素；n為0~4之整數)。該化合物能夠與AMPA受體特異性結合，且腦移行性極高。
