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תרכובת חדשה אשר נקשרת ספציפית לקולטן ל– ampa
专利权人:
SUHARA Tetsuya;PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY;TAKAHASHI Takuya;CHO Meiei;;HIGUCHI Makoto;MIYAZAKI Tomoyuki;
发明人:
TAKAHASHI Takuya,MIYAZAKI Tomoyuki,SUHARA Tetsuya,HIGUCHI Makoto,CHO Meiei
申请号:
IL25673518
公开号:
IL256735D0
申请日:
2018.01.04
申请国别(地区):
IL
年份:
2018
代理人:
摘要:
The present invention provides a compound represented by formula (I), a pharmaceutically acceptable salt thereof or a solvate thereof. (In the formula, each of A and Z independently represents CO, SO or SO 2 ; each of X and Y independently represents S or O; each of R 1 -R 4 independently represents hydrogen, alkyl, alkenyl, alkynyl or halo; each R 5 independently represents alkyl, alkenyl, alkynyl or halo; and n represents an integer of 0-4.) This compound is capable of specifically binding to an AMPA receptor, and shows extremely high brain uptake.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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