<;P>;PROBLEM TO BE SOLVED: To provide an excellent lipopolysaccharide having a property different from that of the conventional lipopolysaccharide of Pantoea agglomerans of wheat, to provide an extract containing the lipopolysaccharide, and to provide the application product thereof. <;P>;SOLUTION: The lipopolysaccharide is obtained from a Gram-negative bacterium living together with a rice plant. The lipopolysaccharide has high Limulus activity, low molecular weight of a subband, a different saccharide chain structure, different lipid A structure, different protain content, saccharide content, nucleic acid content and Limulus active substance content as compared with the conventional lipopolysaccharide of Pantoea agglomerans of wheat and has high preventive effect. <;P>;COPYRIGHT: (C)2011,JPO&INPIT