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STABILIZATION OF IMMUNOGLOBULINS AND OTHER PROTEINS THROUGH AQUEOUS FORMULATIONS WITH SODIUM CHLORIDE AT WEAK ACIDIC TO NEUTRAL ph
专利权人:
Harald Arno Butterweck
发明人:
Harald Arno Butterweck,Theresa Friederike Bauer,Lucia Hofbauer,Wolfgang Teschner,Oliver Zoechling,Hans-Peter Schwarz,Christa Mayer,Meinhard Hasslacher
申请号:
US13235307
公开号:
US20120076779A1
申请日:
2011.09.16
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides, among other aspects, storage stabile aqueous formulations of labile proteins at a mildly acidic to neutral pH. The present invention also provides methods for stabilizing a labile therapeutic protein composition at a mildly acidic to neutral pH. Advantageously, the methods and formulations provided herein allow stabile aqueous compositions of labile proteins at mildly acidic to neutral pH useful for parenteral administration.
来源网站:
中国工程科技知识中心
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